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Immunisation of sheep against experimental Pseudomonas aeruginosa dermatitis and fleece‐rot associated body strike
Author(s) -
BURRELL D. H.
Publication year - 1985
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1985.tb14235.x
Subject(s) - lucilia cuprina , serotype , foot rot , pseudomonas aeruginosa , biology , veterinary medicine , myiasis , microbiology and biotechnology , larva , medicine , calliphoridae , bacteria , botany , genetics
SUMMARY: Sheep immunised with an experimental Pseudomonas aeruginosa vaccine and unvaccinated control sheep were challenged by induction of experimental dermatitis with the homologous strain. All of 6 control sheep developed ulcerative dermatitis, and 2 of the 6 challenge sites were struck by larvae of Lucilia cuprina. Neither severe dermatitis nor strike occurred in 6 vaccinated sheep. These results were confirmed in an experimental challenge using 3 different serotypes of P. aeruginosa on each of 3 vaccinated and control sheep, although fly‐strikes did not occur. In a field trial of the same vaccine, none of 26 vaccinated sheep developed severe exudative, fleece‐rot lesions nor were any fly‐struck, whereas 61 of 115 control sheep developed severe, exudative, fleece‐rot lesions, 21 of these becoming struck by L. cuprina. The isolates of P. aeruginosa recovered from the field challenge experiment were a different serotype to that used in the vaccine.

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