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Duration of excretion of virulent Newcastle disease virus following challenge of chickens with different titres of serum antibody to the virus
Author(s) -
WESTBURY H. A.,
PARSONS G.,
ALLAN W. H.
Publication year - 1984
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1984.tb07189.x
Subject(s) - newcastle disease , virus , virulence , titer , excretion , biology , virology , antibody , cloaca , immune system , immunology , endocrinology , biochemistry , anatomy , gene
SUMMARY Virulent Newcastle disease virus (NDV) was isolated from susceptible and immune chickens following intra‐ocular challenge with the Essex 70 strain. Challenge virus was isolated from the trachea and cloaca of susceptible birds until they died 7 to 9 days after challenge. This virus was isolated from immunised chickens for up to 14 days after challenge. The duration of excretion was influenced by the pre‐challenge serum antibody titre to NDV. It persisted longest in chickens with titres of 2 3 to 2 7 and decreased in length and frequency from chickens with titres in the range 2 3 to 2 12 . Chickens with pre‐challenge titres of 2 3 to 2 5 developed 2 to 3 fold increases in post‐challenge titres, whereas those with higher pre‐challenge titres had smaller proportional increases in titre. Excretion of virulent virus from immunised birds should be considered in the development of Newcastle disease control programs. Aust. vet. J. 61 : 44–46