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Serum biochemical changes in calves with Johne's disease
Author(s) -
EMBURY D. H.,
LEPPER A. W. D.
Publication year - 1984
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1984.tb06011.x
Subject(s) - ceruloplasmin , alkaline phosphatase , medicine , endocrinology , biology , amine oxidase (copper containing) , oxidase test , disease , physiology , enzyme , biochemistry , diamine oxidase
SUMMARY Calves clinically affected with experimentally induced Johne's disease exhibited elevation of caeruloplasmin oxidase activity, and marked depression of α‐mannosidase activity during the period when clinical signs of the disease were most prominent. Changes in serum copper levels and alkaline phosphatase activity were closely correlated with the elevation of caeruloplasmin oxidase activity, and depression of α‐mannosidase activity. The pattern of these changes was similar to nutritional and metabolic changes described previously in acute infectious conditions in man and animals.