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Copper storage disease with intravascular haemolysis in a Bedlington terrier
Author(s) -
WATSON A. D. J.,
MIDDLETON D. J.,
ILKIW J. E.
Publication year - 1983
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1983.tb02815.x
Subject(s) - haemolysis , vomiting , medicine , copper , penicillamine , pathology , gastroenterology , chemistry , immunology , organic chemistry
SUMMARY A 5‐year‐old male Bedlington terrier was found to have haemogloblnuria from intravascular haemolysis. The owners reported also recent vomiting, occasional diarrhoea, reduced activity and increased drinking and urination. A diagnosis of inherited copper storage disease, as previously described in this breed, was established by demonstrating characteristic light and electron microscopic changes and copper content of 7, 717 pg/g in biopsied liver. Treatment by chelation with d‐penicillamine and a low copper diet was instituted and the dog remains well 10 months later. Intravascular haemolysis is rare in dogs and an uncommon finding in Bedlington terriers with copper storage disease.