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STILBOESTROL TOXICITY IN A DOG
Author(s) -
Mills J. N.,
Slatter D. H.
Publication year - 1981
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1981.tb07083.x
Subject(s) - leukocytosis , medicine , toxicity , hyperplasia , diethylstilbestrol , prostate , epididymitis , prostatitis , aplasia , urology , surgery , gastroenterology , hormone , cancer
A case of stilboestrol toxicity is described in a dog which was treated for prostatic hyperplasia with stilboestrol dipropionate (10 mg) daily for 5 days. An initial anaemia and thrombocytopaenia of 19,500/μl was recorded on day 11, and a severe leukocytosis of 125,300/μl on day 15 was followed by a precipitous drop to 8,400/μl on day 21. The dog received antibiotic treatment for concurrent peritonitis and prostatitis/cystitis between days 7 and 15. The dog died on day 41 with marrow aplasia.