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CLINICAL SIGNS, RADIOLOGY AND TISSUE LEAD DISTRIBUTION OF DOGS ADMINISTERED A MIXTURE OF LEAD CHLORIDE, LEAD BROMIDE AND LEAD SULPHATE
Author(s) -
Hamir A. N.,
Sullivan N. D.,
Handson P. D.,
Wilkinson J. S.,
Lavelle R. B.
Publication year - 1981
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1981.tb00542.x
Subject(s) - lead (geology) , lead chloride , lead poisoning , bromide , medicine , chloride , chemistry , biology , inorganic chemistry , paleontology , organic chemistry , psychiatry
SUMMARY Eight‐month‐old dogs maintained on a high‐fat‐low‐calcium diet were administered a mixture of lead chloride, lead bromide and lead sulphate for prolonged periods at 4 different dose levels. Dogs on high levels of lead showed marked weight loss and gastrointestinal symptoms followed by death. Two dogs on low lead levels developed neurological signs. Radiological investigations showed radiopaque particles in 27 per cent of abdominal radiographs and ‘lead lines’ in the distal radius of 3 dogs. Highest tissue lead levels were found in bones followed by liver and kidney, brain and spinal cord.