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A STUDY OF VIRUS‐LIKE PARTICLES PRESENT IN BOVINE NERVE SHEATH TUMOURS
Author(s) -
Canfield P. J.,
Doughty F. R.
Publication year - 1980
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1980.tb05718.x
Subject(s) - virus , budding , transmission electron microscopy , electron microscope , virology , biophysics , biology , tissue culture , morphology (biology) , chemistry , pathology , microbiology and biotechnology , materials science , in vitro , medicine , nanotechnology , biochemistry , physics , optics , genetics
The morphology of virus‐like particles present in bovine nerve sheath tumours is described, and their origin and significance discussed. Virus‐like particles were investigated using transmission electron microscopy and tissue culture. The particles were found in a number of tumours and were present either as aggregates in pseudonuclear inclusions or as budding forms associated with the plasma membrane. The latter were found only in cultured tissue. Although other cellular structures were considered it was thought that the particles represented virus, with those in pseudonuclear inclusions being an intermediate form. Both bovine syncytial virus and oncovirinae were considered as possibilities in the aetiology of the condition.