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EFFECTIVENESS OF ANTHELMINTIC TREATMENTS AGAINST LEVAMISOLE‐RESISTANT OSTERTAGIA
Author(s) -
Jambre L. F. Le
Publication year - 1979
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1979.tb15164.x
Subject(s) - levamisole , oxfendazole , anthelmintic , albendazole , population , biology , veterinary medicine , dose rate , zoology , toxicology , medicine , immunology , fenbendazole , ecology , environmental health , medical physics
SUMMARY: Adult worms from a population of Ostertagia consisting of 88% O. circumcincta and 12% O. trifurcata were found to survive a double drench (14 mg/kg) of levamisole. An anthelmintic assay on this population found that against levamisole the LD 50 was 11.95 mg/kg and the LD 99 was 67.75 mg/kg. Three benzimidazoles were also tested against this population and the LD 50 and LD 99 were respectively thiabendazole 11.8 and 144.9 mg/kg, oxfendazole 0.17 and 6.10 mg/kg and albendazole 0.08 and 2.55 mg/kg. The percentage of worms killed by the recommended dose rate was levamisole 24%; thiabendazole 91%; oxfendazole 99% and albendazole 99%.