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IMMUNITY IN CATTLE TO BABESIA BOVIS AFTER SINGLE INFECTIONS WITH PARASITES OF VARIOUS ORIGIN
Author(s) -
Mahoney D. F.,
Wright I. G.,
Goodger B. V.
Publication year - 1979
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1979.tb09535.x
Subject(s) - babesia bovis , inoculation , biology , vaccination , babesiosis , virulence , virology , heterologous , immunity , immunogenicity , tick infestation , immune system , attenuated vaccine , tick , microbiology and biotechnology , veterinary medicine , immunology , medicine , biochemistry , gene
Sixty calves, 3 to 6 months old, were vaccinated once against Babesia bovis in groups of 10, by the following methods: (a) tick infestation; (b) inoculation of virulent parasites obtained from the tick‐infested animals immediately after infection; (c) inoculation of the parasites used in (b) attenuated by passage through splenectomised calves; (d) inoculation of commercially‐available, living, attenuated vaccine; (e) inoculation of virulent parasites obtained from the tick‐infested animals in (a) one year after infection; (f) inoculation of the parasites used in (e) attenuated by passage. All vaccinated animals were maintained tick‐free and were strongly immune to challenge with a heterologous strain of B. bovis approximately 4 years after vaccination. There was no difference in immunogenicity between any of the B. bovis populations.