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USE OF EDTA BLOOD SAMPLES FOR MANNOSIDOSIS TESTING
Author(s) -
Healy P.J.,
Butrej P.J.
Publication year - 1979
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1979.tb07022.x
Subject(s) - chelation , chemistry , edetic acid , alpha (finance) , biochemistry , chromatography , medicine , surgery , inorganic chemistry , construct validity , patient satisfaction
Preincubation of EDTA plasma with 4mM ZnCI 2 restores acidic alpha mannosidase activity, previously inhibited as a result of chelation of Zn ++ by EDTA. This allows estimation of acidic alpha mannosidase activity in EDTA plasma samples, followed by granulocyte tests on those samples with low activities.