Premium
KERATOCONJUNCTIVITIS SICCA IN DOGS ASSOCIATED WITH SULPHONAMIDE ADMINISTRATION
Author(s) -
Slatter D. H.,
Blogg J. R.
Publication year - 1978
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1978.tb05575.x
Subject(s) - keratoconjunctivitis sicca , keratoconjunctivitis , medicine , administration (probate law) , dermatology , political science , law
SUMMARY: This report describes the clinical characteristics of 14 cases of sulphonamide‐induced keratoconjuctivitis sicca in dogs. Two drugs, sulphadiazine and salicylazosulphapyridine, were associated with the disease. It is recommended that Schirmer Tear Test be performed regularly when sulphonamides are administered long term to dogs. The hypothesis that a nitrogen‐containing pyridine ring is responsible for the lacrimotoxic effect is advanced.