Premium
EVALUATION OF TESTS FOR THE DIAGNOSIS OF LEAD EXPOSURE IN SHEEP
Author(s) -
Rolton Christine E.,
Horton B. J.,
Pass D. A.
Publication year - 1978
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1978.tb02512.x
Subject(s) - lead (geology) , medicine , biology , paleontology
SUMMARY Several laboratory tests that are currently used for the diagnosis of lead poisoning in man were evaluated for the detection of lead poisoning in sheep given 3 or 10 mg Pb/kg body weight/day for 7 weeks. Urinary porphyrins and basophilic stippling of erythrocytes were not sensitive indicators of lead poisoning in sheep, while urinary lead and urinary ∂‐aminolevulinic acid concentrations were too variable to have diagnostic value. However, erythrocyte ∂‐aminolevulinic acid dehydratase was strongly inhibited by exposure to relatively low doses of lead, while blood lead concentrations gave an indication of the level of exposure to lead poisoning.