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THE EFFECT OF DERMALLY APPLIED LEVAMISOLE AGAINST THE PARASITIC NEMATODES OF CATTLE
Author(s) -
Curr C.
Publication year - 1977
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1977.tb05490.x
Subject(s) - levamisole , anthelmintic , ostertagia ostertagi , ostertagia , biology , veterinary medicine , zoology , trichostrongylus , helminths , toxicology , immunology , medicine
SUMMARY A series of trials to establish the anthelmintic efficiency of levamisole, when applied dermally to calves, is described. The levamisole base was formulated in a suitable solvent system at 100 g/ and applied dermally at a dose rate of 8 mg base/kg. This gave efficiencies of 97.1–100%, 88.5–100%, 100%, 98.7–100% and 89.2–100% against adult Haemonchus placei, Ostertagia spp, Cooperia spp, Oesophagostomum radiatum and Trichostrongylus axei , respectively. Activity against the immature stages of H. placei was recorded as 100%, and against immature Cooperia spp the range was 96.3–100%. Extremely variable results were obtained against immature Ostertagia spp, efficiency ranging from 0% to 100%. Efficiency against adult Dictyocaulus viviparus was in the range of 84–100%. The potential advantage of a dermally applied anthelmintic is discussed.