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BOVINE VIBRIOSIS VACCINATION
Author(s) -
Johns D. R.,
Mater R. J.,
Medveczky N. E.
Publication year - 1977
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1977.tb05461.x
Subject(s) - heterologous , biology , serology , vagina , vaccination , homologous chromosome , microbiology and biotechnology , virology , campylobacter fetus , antibody , fetus , adjuvant , strain (injury) , pregnancy , immunology , anatomy , biochemistry , genetics , gene
SUMMARY An adjuvant vaccine was prepared from an Australian isolate of Campylobacter fetus subsp fetus biotype intermedius and injected into 23 virgin Guernsey heifers. Ten nonvaccinated animals served as controls. When challenged by the intravaginal route with a culture of either the homologous strain or biotype venerealis , weekly swabs from the anterior vagina continued to yield either biotype in 8 of 10 nonvaccinates at 6 weeks as compared with 3 of 23 vaccinates. Serology in vaccinated heifers and rabbits showed that the vaccine produced high titres of antibody against both homologous and heterologous strains.