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OBSERVATIONS OF SW AINSONA GALEGIFOLIA POISONING IN CATTLE IN NORTHERN NEW SOUTH WALES
Author(s) -
Hartley W. J.,
Gibson A. J. F.
Publication year - 1971
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1971.tb15497.x
Subject(s) - virus , infiltration (hvac) , lung , mononuclear cell infiltration , respiratory system , pathology , pneumonia , inoculation , biology , peripheral blood mononuclear cell , lymph , lymph node , interstitial pneumonia , virology , necrosis , medicine , anatomy , biochemistry , physics , in vitro , thermodynamics
Summary A mild interstitial pneumonia with mononuclear cell infiltration was produced in calves following intra‐tracheal inoculation of the BIL adenovirus. Viral antigen appeared early in the regional lymph node. An interstitial reaction developed early in the lungs, and pneumonic lesions and infective virus were present by the third day after inoculation. Virus spread rapidly to trachea, tonsils and nasal mucosa, and was excreted from the third to eighth day. Upper and lower respiratory tissues continually harboured virus until the 12th day, when the experiment was terminated. The virus was isolated from the livers of two calves. All tissues yielded low concentrations of virus, and only the lung showed pathological reactions. The reactions were qualitatively similar to known adenovirus pneumonias, but considerably milder, and lacked the characteristic necrotic and proliferative bronchiolar changes.