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GC‐MS Determined Distribution of Urinary Equol Producers as Affected by Age, Gender, and Repeated Ingestions of Soymilk
Author(s) -
Ko TingFu,
Tsai HuiSu,
Lin ShuMei,
Liu ChiDong,
Learn ShowPhon,
Chiou Robin Y.Y.
Publication year - 2010
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1750-3841.2010.01860.x
Subject(s) - equol , ingestion , isoflavones , medicine , excretion , urine , incidence (geometry) , food science , physiology , chemistry , daidzein , genistein , physics , optics
Status of equol excretion is likely a reflection of incidence risk of sex‐hormone related diseases and deserves research attention. In this study, urine samples collected from 182 volunteers after soymilk ingestion were subjected to equol quantification using GC‐MS. As categorized into male, female, and both genders and each category further classified into 6 age (year) categories, namely, <20, 21 to 30, 31 to 40, 41 to 50, >51 and overall, a trend indicating that the younger age the higher equol producer ratio was observed. For the >51 subjects, the corresponding producer ratios of males and females were 35.3% and 50.0%, respectively. Among the volunteers, 20 nonproducers were further recruited to ingest 1000 mL soymilk weekly for 16 wk and urines were analyzed bi‐weekly. As resulted, 8 of 20 nonproducers were induced to become equol producers. The observed change of nonproducers to equol producers induced by repeating ingestions of soymilk is of merit from the viewpoint of healthcare. Practical Application: Excretion of equol after ingestion of isoflavones‐containing foods is likely to bear lower incidence risk of sex‐hormone related diseases, which attracts public attention. Based on observed possibility that nonproducers could be induced to become equol producers by repeating ingestions of soymilk, frequent intake of soybean‐derived foods is recommended.