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β‐Carotene‐Loaded Nanostructured Lipid Carriers
Author(s) -
Hentschel A.,
Gramdorf S.,
Müller R.H.,
Kurz T.
Publication year - 2008
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/j.1750-3841.2007.00641.x
Subject(s) - differential scanning calorimetry , particle size , materials science , chemical engineering , colloid , ingredient , nanoparticle , suspension (topology) , chromatography , chemistry , nanotechnology , organic chemistry , food science , physics , homotopy , pure mathematics , engineering , thermodynamics , mathematics
Nanostructured lipid carriers (NLC) technology was used to disperse hydrophobic β‐carotene in an aqueous phase. NLC are lipid nanoparticles with a particle matrix consisting of a blend of a liquid and solid lipid. They were produced by melting the lipid blend at 80 °C and dispersing it into a hot emulsifier solution. The aim of this study was to extend the limited knowledge of melt‐emulsified lipidic colloids in food systems and to evaluate the feasibility for further applications as functional ingredient in beverages. Physical stability of the NLC suspension was examined at 2 different storage temperatures by measuring the particle size with photon correlation spectroscopy (PCS) and laser diffractometry (LD). All particles containing sufficient amounts of emulsifier were smaller than 1 μm (LD diameter 100%) at a mean particle size of around 0.3 μm (LD) for 9 wk at 20 °C and at least 30 wk at 4 to 8 ° C. Differential scanning calorimetry (DSC) was used to study the solid state of the lipids both in the β‐carotene loaded PGMS and in the NLC particles. Propylene glycol monostearate (PGMS) when dispersed as NLC recrystallized up to 98% during storage time. Within the regarded period of 7 mo no polymorph transitions were observed. Furthermore, stability of the β‐carotene in water dependent on NLC concentration and tocopherol content was measured photospectrometrically to get an estimation of the behavior of NLC in beverages.