Open Access23‐YEAR‐OLD MAN WITH A SUPERFICIAL CORTICAL BRAIN TUMOR
Author(s) -
Costa Sónia,
Marques Joana,
Pereira Pedro,
Firmo Carla,
Pimentel José
Publication year - 2012
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/j.1750-3639.2012.00590.x
Subject(s) - ganglioglioma , pleomorphic xanthoastrocytoma , pathology , astrocytoma , medicine , differential diagnosis , immunohistochemistry , nodule (geology) , anatomy , biology , epilepsy , glioblastoma , paleontology , cancer research , psychiatry
A 23-year-old male presented with a tonic-clonic generalized seizure. Neuroradiological examination revealed a superficial cystic mass with a mural nodule in the right fronto-parietal lobe. Histological and immunohistochemical examination were consistent with a pigmented (melanin producing) desmoplastic ganglioglioma.These tumors have been first described in childhood, one of them displaying melanin deposits. Only twenty cases of non-infantile desmoplastic gangliogliomas have been reported in the literature, none of them pigmented. According to the clinical and histomorphology (including the desmoplastic component) features, the differential diagnosis should include the ganglioglioma, the xanthoastrocytoma pleomorphic (both tumors also with pigmented forms) and the superficial desmoplastic infantile astrocytoma.