Open AccessA 54‐YEAR‐OLD WOMAN WITH A MENINGEAL LESION COMPRESSING THE MEDULLA OBLONGATA
Author(s) -
Kolodziej Malgorzata,
Benes Ludwig,
Nimsky Christopher,
Schaefer HansEckart,
Pagenstecher Axel
Publication year - 2010
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/j.1750-3639.2010.00434.x
Subject(s) - medicine , lesion , medulla oblongata , paresis , meninges , ataxia , vomiting , prednisolone , foramen magnum , pathology , vasculitis , radiology , surgery , central nervous system , disease , psychiatry
A 54-year-old woman had nausea, vomiting and personality changes since a few weeks. Paresis of the abducens and hypoglossal nerves on the left side, a right sided reduction of the visual field, discrete dysarthri×a and ataxia were diagnosed. Cranial magnetic resonance imaging demonstrated a contrast enhancing circular meningeal lesion of the foramen magnum. Histological examination revealed a granulomatous lesion of the meninges with focal necrosis, vasculitis and neutrophils indicating immune complex reactions. A diagnosis of primary meningeal Wegener's disease was made. Medication with low dose prednisolone led to complete remission of the lesion 1.5 years later.