Open AccessA 22‐YEAR‐OLD MAN WITH INTRACRANEAL HYPERTENSION AND IMPAIRED SENSATION OVER THE PERINEUM AND LEFT FOOT
Author(s) -
Foreid Henda,
Barroso Cândida,
Carvalho Herculano,
Morgado Carlos,
Roque Lúcia,
Pimentel José
Publication year - 2009
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/j.1750-3639.2009.00312.x
Subject(s) - medicine , medulloblastoma , primitive neuroectodermal tumor , pathology , immunohistochemistry
Primary leptomeningeal tumors are rare and can have multiple origins. This young man presented an intracranial hypertension syndrome and brain MRI features of diffuse leptomeningeal enhancement over cerebral and cerebellar hemispheres. A second cerebellar biopsy allowed the diagnosis of a primary diffuse leptomeningeal Primitive Neuroectodermal Tumor (PNET). Besides the paucity of reports of primary leptomeningeal PNET, its differentiation from primary leptomeningeal medulloblastomas is not always clear-cut and is discussed.