Open AccessCASE OF THE MONTH: February 1999 ‐ 54 Year Old Man with Severe Muscle Weakness
Author(s) -
Hill Michael D,
Bilbao Juan M
Publication year - 1999
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/j.1750-3639.1999.tb00607.x
Subject(s) - neuropathology , citation , library science , sociology , history , medicine , computer science , pathology , disease
A 54 year old man developed rhabdomyolysis one year after beginning treatment with a combination of lovastatin (an HMGCoA reductase inhibitor) and niacin. Muscle biopsy showed a severe necrotizing myopathy affecting both fibre types. Recovery occured gradually with cessation of medication. The spectrum of cholesterol lowering agent myopathy may include delayed cases of unusual severity.