Open AccessReference viruses for seasonal and pandemic influenza vaccine preparation
Author(s) -
Wood John M.,
Robertson James S.
Publication year - 2007
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/j.1750-2659.2006.00003.x
Subject(s) - seasonal influenza , pandemic , virology , influenza a virus subtype h5n1 , biology , pandemic influenza , highly pathogenic , covid-19 , influenza vaccine , influenza a virus , virus , medicine , infectious disease (medical specialty) , disease , pathology
The production of seasonal and pandemic influenza vaccines depends on the timely availability of suitable reference viruses. Seasonal vaccines are traditionally produced from high‐growth reassortant viruses, which have been derived empirically using well‐established techniques. However, it is not possible to use such approaches in deriving vaccine reference viruses from highly pathogenic H5N1 viruses and alternative techniques such as reverse genetics must be employed.