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Systems pharmacology of complex diseases
Author(s) -
Hansen Jens,
Zhao Shan,
Iyengar Ravi
Publication year - 2011
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2011.06382.x
Subject(s) - pharmacology , systems pharmacology , medicine , neuroscience , computational biology , biology , drug
Systems pharmacology approaches can be used to identify and predict drug‐induced adverse events. Disease‐centered networks within the human interactome allow us to predict which drugs may produce a similar pathophysiology. Such predictions can be tested in animal models.