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Is it time for in silico simulation of drug cardiac side effects?
Author(s) -
Mirams Gary R.,
Noble Denis
Publication year - 2011
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2011.06324.x
Subject(s) - in silico , drug , drug action , action (physics) , computer science , side effect (computer science) , pharmacology , medicine , chemistry , physics , biochemistry , gene , quantum mechanics , programming language
Cardiac simulation is used to integrate information on drug action to predict side effects on the whole heart. Could simulation begin to replace animal models?