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Stem cell engineering: limitation, alternatives, and insight
Author(s) -
Lim Jeong Mook,
Lee Myungook,
Lee Eun Ju,
Gong Seung Pyo,
Lee Seung Tae
Publication year - 2011
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2011.06093.x
Subject(s) - risk analysis (engineering) , stem cell , progenitor cell , stem cell therapy , computer science , intensive care medicine , medicine , biochemical engineering , engineering ethics , engineering , biology , genetics
The 21st century will see improvements in the quality of human life. The development of new therapeutic technologies will prevent prevalent diseases and enable recovery from currently incurable diseases. The development of cell and tissue replacement therapies using stem cells and their progenitors will accelerate the development of causative treatments. The effort expended thus far in developing cell therapies has revealed many technical limitations. Thus, we must explore conceptual changes in the feasibility of stem cell therapy. This paper introduces the current limitations to stem cell engineering and ways to overcome these limitations, which will provide new insight into their clinical application.