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The esophagogastric junction
Author(s) -
Miller Larry S.,
Vegesna Anil K.,
Brasseur James G.,
Braverman Alan S.,
Ruggieri Michael R.
Publication year - 2011
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2011.06073.x
Subject(s) - esophagogastric junction , gerd , gastroesophageal junction , esophagus , reflux , stomach , medicine , gastroenterology , pathophysiology , anatomy , adenocarcinoma , disease , cancer
The following discussion of the esophagogastric junctions includes commentaries on the three component structures of the sphincteric segment between the stomach and the esophagus; the pressure contributions from the three sphincteric components in normal subjects and in gastroesophageal reflux (GERD) patients; the mechanism of action of endoscopic plication to determine the underlying pathophysiology of GERD; and in vitro muscle strip studies of defects within the gastroesophageal sphincteric segment potentially leading to GERD.