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Rheumatic diseases and Klinefelter's syndrome
Author(s) -
Rovenský J.,
Imrich R.,
Lazúrová I.,
Payer J.
Publication year - 2010
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2009.05292.x
Subject(s) - medicine , polymyositis , dermatology , dermatomyositis , ankylosing spondylitis , rheumatoid arthritis , mixed connective tissue disease , psoriatic arthritis , scleroderma (fungus) , connective tissue disorder , arthritis , immunology , pathology , inoculation
The article summarizes reports on the concurrence of Klinefelter's syndrome (KS) with inflammatory rheumatic diseases, rheumatoid arthritis (RA), juvenile idiopathic arthritis, psoriatic arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, systemic sclerosis, mixed connective tissue disease, the antiphospholipid syndrome, and ankylosing spondylitis. These include two case reports of patients with KS concurrently associated with RA or antisynthetase syndrome, respectively, previously reported by the author and his coworkers. Attention is paid to the pathogenesis and the course of the disease in patients with KS. The importance of early diagnosis of the syndrome, when occurring simultaneously with other diseases of connective tissue, is emphasized.