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Circadian Expression of Clock Genes Clock and Cry1 in the Embryonic Chicken Pineal Gland
Author(s) -
Nagy Andras D.,
Kommedal Siri,
Seomangal Karishma,
Csernus Valer J.
Publication year - 2009
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2008.03639.x
Subject(s) - circadian rhythm , biology , pineal gland , clock , circadian clock , period (music) , embryonic stem cell , embryogenesis , gene expression , microbiology and biotechnology , embryo , medicine , endocrinology , gene , genetics , physics , acoustics
Clock and Cry1 expression were examined in the pineal gland of chicken embryos incubated under constant darkness from embryonic day (ED) 0. From ED13, Clock and Cry1 mRNA levels showed episodic alterations. After ED17, circadian pattern of clock gene expression was seen both in vivo and in vitro . Our results support the idea that rhythmic environmental factors are not necessary for the generation of circadian patterns of clock gene expression during development.