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Marrow Stem Cell Potential within a Continuum
Author(s) -
QUESENBERRY P.,
COLVIN G.,
LAMBERT J. F.,
ABEDI M.,
CERNY J.,
DOONER M.,
MOORE B.,
McAULIFFE C.,
DEMERS D.,
GREER D.,
PARENT A.,
BADIAVAS E.,
LUM L.,
FALANGA V.
Publication year - 2003
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2003.tb03248.x
Subject(s) - stem cell , haematopoiesis , biology , stem cell biology , microbiology and biotechnology , hematopoietic stem cell , phenotype , developmental biology , cell cycle , cell , stem cell factor , genetics , gene , embryo , reproductive technology , embryogenesis
A bstract : On the basis of our studies of the fluctuation of the hematopoietic stem cell phenotype with cell cycle trnsit, we hypothesize that the ability of marrow stem cells to convert to nonhematopoietic cells will also vary at different points in the cell cycle. The new biology of stem cells has an impact on many fields including developmental biology and stem cell biology and the clinical potential is enormous.