Premium
Lymphangiogenesis New Mechanisms
Author(s) -
CHANG LYNN,
KAIPAINEN ARJA,
FOLKMAN JUDAH
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04872.x
Subject(s) - lymphangiogenesis , angiogenesis , microbiology and biotechnology , vegf receptors , cancer research , chemistry , medicine , biology , metastasis , cancer
A bstract : A mouse model has been developed to study lymphangiogenesis dissociated from angiogenesis. bFGF implanted in a mouse cornea at a concentration below the threshold to induce angiogenesis potently induces lymphangiogenesis. This model has permitted a study of cellular and molecular mechanisms of lymphangiogenesis.