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Steroid Receptors in Various Glial Cell Lines Expression and Functional Studies
Author(s) -
CADEPOND FRANÇOISE,
MASSAAD CHARBEL,
TROUSSON AMALIA,
GRENIER JULIEN,
GROYER GHISLAINE,
BAULIEU ETIENNE,
SCHUMACHER MICHAEL
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04689.x
Subject(s) - receptor , glucocorticoid receptor , messenger rna , biology , microbiology and biotechnology , central nervous system , cell culture , steroid , endocrinology , genetics , gene , hormone
A bstract : In glial cell lines from the central (CG4, C6) and peripheral (MSC80, CR3a1, and CR1b4) nervous systems, glucocorticoid receptor (GR) messenger RNA was clearly detected and was consistent with significant GR binding and transcriptional activity. Mineralocorticosteroid receptor mRNA was less abundant, with no corresponding binding and lack of transcriptional activity. Other steroid receptors were not significantly detected.