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Extracellular ATP Induces Phosphatidylserine Externalization Earlier than Nuclear Apoptotic Events in Thymocytes
Author(s) -
COURAGEOT MARIEPIERRE,
LEPINE SANDRINE,
GIRAUD FRANCOISE,
SULPICE JEANCLAUDE
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04630.x
Subject(s) - phosphatidylserine , extracellular , microbiology and biotechnology , apoptosis , externalization , chemistry , caspase , biophysics , programmed cell death , biology , biochemistry , psychology , phospholipid , membrane , psychoanalysis
A bstract : The present study shows for the first time that ATP ec induces a very early PS exposure in thymocytes and that this process can be induced in the absence of Ca 2+ influx and caspase activation.