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Activation of the p38 MAPK and ERK1/2 Pathways Is Required for Fas‐Induced IL‐8 Production in Colonic Epithelial Cells
Author(s) -
O'BRIEN DARREN,
O'CONNOR TERRY,
SHANAHAN FERGUS,
O'CONNELL JOE
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04627.x
Subject(s) - microbiology and biotechnology , chemistry , p38 mitogen activated protein kinases , mapk/erk pathway , signal transduction , biology
A bstract : This paper aims to examine the contribution of all three of the MAP kinase signaling pathways to Fas‐induced IL‐8 up‐regulation in HT29 colon epithelial cells.