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New Structure Involved in Transient Membrane Fusion and Exocytosis
Author(s) -
CHO SJ.,
WAKADE A.,
PAPPAS G. D.,
JENA B. P.
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04471.x
Subject(s) - exocytosis , membrane , vesicle , lipid bilayer fusion , microbiology and biotechnology , secretory vesicle , chemistry , biophysics , vesicle fusion , fusion , biology , biochemistry , synaptic vesicle , linguistics , philosophy
A bstract : Our studies using atomic force microscopy (AFM) reveal a new group of plasma membrane structures involved in exocytosis in live pancreatic acinar cells. These studies demonstrate that “pits” and “depressions” are sites at the apical plasma membrane in live cells, where membrane‐bound secretory vesicles dock and transiently fuse to release vesicular contents.