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Hypertension in Congenital Adrenal Hyperplasia and Apparent Mineralocorticoid Excess
Author(s) -
NEW MARIA I.
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb04420.x
Subject(s) - plasma renin activity , endocrinology , medicine , hormone , blood pressure , renovascular hypertension , context (archaeology) , renin–angiotensin system , aldosterone , endocrine system , hyperaldosteronism , mineralocorticoid , congenital adrenal hyperplasia , biology , paleontology
A bstract : Most often, low‐renin hypertension in the child or adolescent has a clearly definable hormonal cause; thus while each of its numerous forms is moderately rare, a specific hormonal basis is to be expected. An endocrine evaluation is indicated after exclusion of cardiologic pathology or renovascular or portal abnormality in a hypertensive child. The evaluation should include analysis of catecholamine and of thyroid hormone plasma levels, and plasma renin activity (PRA) level. Hormonal hypertension with high or normal renin conditions is rare. Elevated blood pressure with high or normal renin levels may be in fact within normal range in the context of growth at upper percentile limits, possibly in conjunction with simple obesity. Diagnosis may be made at any age in most forms of low‐renin hypertension.