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Biomaterials and Scaffolds in Reparative Medicine
Author(s) -
CHAIKOF ELLIO L.,
MATTHEW HOWARD,
KOHN JOACHIM,
MIKOS ANTONIO G.,
PRESTWICH GLENN D.,
YIP CHRISTOPHER M.
Publication year - 2002
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2002.tb03057.x
Subject(s) - regenerative medicine , tissue engineering , nanotechnology , computer science , medicine , biomedical engineering , stem cell , biology , materials science , microbiology and biotechnology
A bstract : Most approaches currently pursued or contemplated within the framework of reparative medicine, including cell‐based therapies, artificial organs, and engineered living tissues, are dependent on our ability to synthesize or otherwise generate novel materials, fabricate or assemble materials into appropriate 2‐D and 3‐D forms, and precisely tailor material‐related physical and biological properties so as to achieve a desired clinical response. This paper summarizes the scientific and technological opportunities within the fields of biomaterials science and molecular engineering that will likely establish new enabling technologies for cellular and molecular therapies directed at the repair, replacement, or reconstruction of diseased or damaged organs and tissues.