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Role of Steroid Hormone‐Regulated Genes in Implantation
Author(s) -
BAGCHI INDRANI C.,
LI QUANXI,
CHEON YONG PIL
Publication year - 2001
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2001.tb03792.x
Subject(s) - endometrium , steroid , hormone , steroid hormone , estrogen , embryo , endocrinology , receptivity , biology , medicine , microbiology and biotechnology
The endometrium acquires the ability to implant the developing embryo within a specific time window, termed the “receptive phase.” During this period, the endometrium undergoes pronounced structural and functional changes induced by the ovarian steroids, estrogen and progesterone, which prepare it to be receptive to invasion by the embryo. These steroid‐induced molecules, when identified, may serve as useful markers of uterine receptivity. In this article, we provide a brief description of one such molecule that has emerged as candidate marker of steroid hormone action in rats and humans during implantation.