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Platelet Adhesion to Fibrinogen Coated at Various Densities
Author(s) -
JIROUŠKOVÁ MARKÉTA,
COLLER BARRY S.
Publication year - 2001
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2001.tb03532.x
Subject(s) - fibrinogen , syk , platelet , adhesion , chemistry , platelet adhesiveness , integrin , tyrosine phosphorylation , phosphorylation , tyrosine , platelet adhesion , cell adhesion , platelet activation , microbiology and biotechnology , biophysics , platelet aggregation , immunology , biochemistry , tyrosine kinase , medicine , signal transduction , biology , cell , organic chemistry
A bstract : Platelet adhesion to low‐density coated fibrinogen induces greater protein tyrosine phosphorylation of SYK and FAK than adhesion to high‐density coated fibrinogen, and leads to activation of integrin αIIbβ3 on the luminal side of adherent platelets.