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Culture Models of Neurodegenerative Disease
Author(s) -
FIGLEWICZ D. A.,
DONG L.,
MLODZIENSKI M.,
TURCOTTE J. C.
Publication year - 2000
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2000.tb06873.x
Subject(s) - stressor , neuroscience , disease , sod1 , order (exchange) , biology , computer science , amyotrophic lateral sclerosis , medicine , business , finance
A bstract : In order to investigate how mutant SOD1 protein or environmental exogenous stressors lead to the death of motor neurons, we have established several in vitro model systems. We describe some features of the various models in order to demonstrate the advantages and shortcomings of each system.