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In Vivo Determination of Body Composition of Rats Using Magnetic Resonance Imaging
Author(s) -
TANG HAIYING,
VASSELLI JOSEPH,
WU ED,
GALLAGHER DYMPNA
Publication year - 2000
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2000.tb06418.x
Subject(s) - magnetic resonance imaging , in vivo , segmentation , biomedical engineering , adipose tissue , computer science , image segmentation , visualization , nuclear magnetic resonance , artificial intelligence , medicine , radiology , physics , biology , microbiology and biotechnology , endocrinology
A bstract : Magnetic resonance imaging (MRI) has potential as an instrument to measure body composition because it can discriminate various soft tissues in vivo . These soft tissues include adipose tissue, muscle, organs, and brain. We report on preliminary studies using a 4.2‐tesla MRI for measuring body composition in the mouse and rat. We employed image segmentation methods that include an image correction method, a necessary requirement when the images are taken in the presence of nonuniform radio‐frequency (RF) coil response. The software for 3‐D data segmentation, quantification, correction, image manipulation, and visualization has been developed as a research tool. This method currently is being validated.