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Hormone Replacement Therapy and Breast Cancer Risk
Author(s) -
KOUKOULIS GEORGE N.
Publication year - 2000
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2000.tb06256.x
Subject(s) - breast cancer , menopause , hormone replacement therapy (female to male) , medicine , hormone , gynecology , hormonal replacement therapy , drop out , oncology , cancer , obstetrics , economics , demographic economics , testosterone (patch)
A bstract : The female breast is subject to a lifetime of hormonal control. After menopause, breast tissue becomes quiescent when estrogens drop to low levels. Menopause‐associated hormonal decreases produce short‐ and long‐term consequences that can be treated successfully by hormone replacement therapy (HRT). Despite the beneficial effects of HRT, the potential risk of breast cancer is a concern of both women and physicians. The available data indicate that HRT administered for longer than 5 years moderately increases the risk of breast cancer, but overall the benefits outweigh the potential risk.