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Clara Cell Proteins
Author(s) -
SINGH GURMUKH,
KATYAL SIKANDAR L.
Publication year - 2000
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.2000.tb05518.x
Subject(s) - uteroglobin , antiparallel (mathematics) , secretion , secretory protein , in vitro , cell , chemistry , microbiology and biotechnology , amino acid , biochemistry , biology , gene , physics , quantum mechanics , magnetic field
A bstract : Clara cells are nonciliated, nonmucous, secretory cells of the pulmonary airways. These cells are known to secrete a variety of proteins, including Clara cell 10‐kDa protein/uteroglobin. This protein consists of a homodimer of 70–77 amino acid polypeptides arranged in antiparallel fashion. In vitro testing suggests that the protein suppresses inflammation. The physiologic role of the protein remains to be determined.