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Proteins Expressed by Pancreatic Duct Cellsand Their Relatives
Author(s) -
HOLLINGSWORTH MICHAEL A.
Publication year - 1999
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1999.tb09508.x
Subject(s) - pancreatic duct , medicine , pancreas
A bstract : Significant progress has been made in the characterization of the structure and function of pancreatic ductal cells. Our understanding at this point in time extends to knowledge of specific molecules that provide for the structural composition of the ductal cells, their interactions with the local environment, and the regulation of their growth and properties of differentiation. Knowledge of the molecular composition and structure of the secretory products of epithelial cells in the pancreas also has increased so that we now understand the individual contributions of several secretory products to the overall function of pancreatic juice. Further study of these parameters will give us important insight into the normal function of the ductal cells and into how these processes are altered during the development and progression of diseases of the pancreas such as pancreatitis and cancer.