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Oxidized LDL and Atherogenesis a
Author(s) -
YLÄHERTTUALA SEPPO
Publication year - 1999
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1999.tb09231.x
Subject(s) - lipid peroxidation , lesion , inflammation , oxidative damage , chemistry , oxidative phosphorylation , arterial wall , oxidative stress , biochemistry , medicine , pathology
A bstract : A brief review of recent findings regarding the role of oxidized low‐density lipoproteins (Ox‐LDL) in atherogenesis. Lipid peroxidation and oxidative damage to LDL make arteries susceptible to chronic inflammation, which is known to cause alterations in arterial gene expression and promote lesion development. Treatment protocols implementing antioxidants for preventing cardiovascular diseases are suggested.