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Radiation Sterilization of a Bifunctional Cement Formulation of Hydroxilapatite‐Plaster‐Polymers
Author(s) -
VIDAL DIANELYS SAINZ,
NAPOLES DANIA RODRIGUEZ,
ESTEVEZ GASTON FUENTES,
GUERRA MERCEDES,
SORIANO WILLIAMS ARCIS,
AVES EDUARDO PEON,
ARGOTA JOSE M. DIAZ,
SILVA DIONISIO ZALDIVAR
Publication year - 1999
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1999.tb08494.x
Subject(s) - sterilization (economics) , cement , ionizing radiation , dry heat , materials science , bone cement , waste management , dentistry , medicine , environmental science , pulp and paper industry , composite material , irradiation , business , engineering , physics , finance , exchange rate , nuclear physics , foreign exchange market
A sterilization method based on the use of gamma ionizing radiation was applied to a cement formulation of hydroxilapatite, plaster and polymers to be used in bone restorations in dental, aesthetic, and neurological surgery. After the cement was exposed to a dose of 21.5 kGy it reached the sterility assurance level which was necessary for its employment in surgical applications as specified by International Standard ISO ordinate 11137: Radiation Sterilization of Health Care Products. No variation in the initial cement composition or processing parameters, such as working or setting time and molding quality was observed due to sterilization. Its characteristics as a drug delivery system were also not affected. Therefore, radiation sterilization provides a feasible alternative to conventional sterilization methods such as dry/wet heat and ethylene oxide.