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New Microcapsules Based on Oligoelectrolyte Complexation
Author(s) -
BARTKOWIAK ARTUR,
HUNKELER DAVID
Publication year - 1999
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1999.tb08492.x
Subject(s) - molar mass , chitosan , molar , chemistry , salt (chemistry) , molar ratio , molar concentration , permeability (electromagnetism) , modulus , chemical engineering , chromatography , polymer chemistry , polymer , materials science , organic chemistry , composite material , dentistry , biochemistry , catalysis , medicine , membrane , engineering
ABSTRACT: A new one‐step microencapsulation procedure has been developed. For the alginate/oligochitosan system the molar mass of the chitosan is a key parameter in the formation of stable, elastic capsules with high modulus. Furthermore, the selection of an optimum molar mass provides an additional degree of freedom, permitting the simultaneous regulation of mechanical properties and permeability without the need for multicomponent organic‐inorganic chemistries as have been previously employed. The effects of molar mass of chitosan, its concentration, the alginate molar mass and its metal salt on the preparation, physical properties, and release characteristics of the capsules have been studied.