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Receptor‐Mediated Local Fine‐Tuning by Noradrenergic Innervation of Neuroendocrine and Immune Systems a
Author(s) -
VIZI E. S.
Publication year - 1998
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1998.tb09012.x
Subject(s) - immune system , cytokine , glucocorticoid , glucocorticoid receptor , neuroscience , adrenal cortex , receptor , immunology , endocrinology , medicine , biology
Immune responses can be modulated by noradrenergic input at (1) hypothalamic (CRF and ACTH release), (2) immune cell (cytokine production), and (3) adrenal cortex (glucocorticoid production) level. Elucitating the basic mechanisms responsible for immunological responses and diseases may be helpful in developing therapeutic approaches for many disorders, such as autoimmune diseases.