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Synthetic Strategies for the Preparation of Precursor Polymers and of Microcapsules Suitable for Cellular Entrapment by Polyelectrolyte Complexation of Those Polymers a
Author(s) -
DYAKONOV TANIA A.,
ZHOU LEI,
WAN ZENG,
HUANG BIN,
MENG ZHIZHONG,
GUO XIAOYAN,
ALEXANDER HOLLY,
MOORE WAYNE V.,
STEVENSON WILLIAM T. K.
Publication year - 1997
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1997.tb52185.x
Subject(s) - library science , chemistry , polyelectrolyte , polymer science , organic chemistry , computer science , polymer
The production of microcapsules suitable for the entrapment of mammalian cell by means of polyelectrolyte complexation has, of a necessity, led to the development of novel strategies for the preparation of relatively bioinert polymers which complex efficiently under unique conditions to produce a mechanically resilient membrane with efficient transport properties. In this communication we relate a brief overview of capsule-membrane forming systems for the immunoisolation (or potential immunoisolation) of mammalian cells, which are based upon the complexation of polyelectrolyte (PE) polymers; with emphasis on precursor synthesis and relationships between precursor polymer structure and capsule membrane stability.