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Social Stress, Depression, and Brain Dopamine in Female Cynomolgus Monkeys
Author(s) -
SHIVELY CAROL A.,
GRANT KATHLEEN A.,
EHRENKAUFER RICHARD L.,
MACH ROBERT H.,
NADER MICHAEL A.
Publication year - 1997
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1997.tb51972.x
Subject(s) - dopaminergic , agonistic behaviour , aggression , psychology , anxiety , dopamine , depression (economics) , pathological , neuroscience , dopamine receptor , social stress , developmental psychology , social defeat , clinical psychology , medicine , psychiatry , economics , macroeconomics
Socially subordinate adult female cynomolgus monkeys are hypercortisolemic, the targets of aggression, fearful, vigilant, receive little positive affiliative contact, exhibit pathological behaviors indicating anxiety, and are disengaged in the social events around them. Subordinates also have altered dopaminergic activity that may be due to decreased D2 receptor binding. Dopaminergic activity indices were more closely associated with affiliative than agonistic behaviors.