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New Histological and Physiological Stains Derived from Diffusion‐Tensor MR Images
Author(s) -
BASSER PETER J.
Publication year - 1997
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1997.tb46192.x
Subject(s) - diffusion mri , scaling , isotropy , diffusion , statistical physics , homogenization (climate) , measure (data warehouse) , anomalous diffusion , effective diffusion coefficient , term (time) , physics , mathematical analysis , mathematics , computer science , optics , magnetic resonance imaging , geometry , data mining , ecology , knowledge management , innovation diffusion , biology , radiology , thermodynamics , quantum mechanics , medicine , biodiversity
The measurement of the self-diffusivity of water (and other solvents) using the phenomenon of nuclear magnetic resonance was first reported more than four decades ago. Methodological improvements in these diffusion measurements2 and the subsequent development of magnetic resonance imaging,' together created the possibility to measure diffusion properties of water in tissues on a voxel by voxel basis. Diffusion imaging (DI), which was first realized in 1985,4-6 consists of measuring an apparent diffusion constant (ADC)7 in each voxel. Both its theoretical underpinnings and its applications are well-known and are described in a number of excellent books and review